This clue appeared in the NYT Crossword on Sunday, April 26, 2026 (12 Down). The answer is hidden below until you want it. Sunday puzzles are large (21 by 21) and themed, about as hard as a Wednesday or Thursday.
Answer length: 3 squares
First letter
L _ _
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About the answer
LSD as a word: (organic chemistry) Abbreviation of lysergic acid diethylamide. [(organic chemistry) A powerful synthetic hallucinogen.]; Initialism of Lake Shore Drive (freeway in Chicago).
LSD has been an answer 13 times in the NYT Crossword and Mini since November 8, 2025.
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