This clue appeared in the NYT Crossword on Wednesday, December 3, 2025 (33 Down). The answer is hidden below until you want it. Wednesday sits mid-week in difficulty, with more wordplay than Monday or Tuesday.
Answer length: 3 squares
First letter
L _ _
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About the answer
LSD as a word: (organic chemistry) Abbreviation of lysergic acid diethylamide. [(organic chemistry) A powerful synthetic hallucinogen.]; Initialism of Lake Shore Drive (freeway in Chicago).
LSD has been an answer 13 times in the NYT Crossword and Mini since November 8, 2025.
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