This clue appeared in the NYT Crossword on Saturday, November 8, 2025 (55 Down). The answer is hidden below until you want it. Saturday puzzles are the hardest of the week and themeless, so clues are often deliberately misleading.
How to read this clue
"Abbr." or "for short" means the answer is itself an abbreviation or a shortened form.
Answer length: 3 squares
First letter
L _ _
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About the answer
LSD as a word: (organic chemistry) Abbreviation of lysergic acid diethylamide. [(organic chemistry) A powerful synthetic hallucinogen.]; Initialism of Lake Shore Drive (freeway in Chicago).
LSD has been an answer 13 times in the NYT Crossword and Mini since November 8, 2025.
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