This clue appeared in the NYT Crossword on Tuesday, December 9, 2025 (46 Across). The answer is hidden below until you want it. Tuesday puzzles are a step up from Monday but still mostly straightforward.
Answer length: 3 squares
First letter
I _ _
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About the answer
ISO as a word: Quarantine measures in order to mitigate the spread of communicable diseases, such as Covid-19; (American football, basketball) An isolation play in basketball or American football.
ISO has been an answer 5 times in the NYT Crossword and Mini since November 12, 2025.
Other clues with the same answer
More clues from this puzzle
- Verdant privacy features … or a punny description of the four longest answers in this puzzle (35 Across)
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- Historical (41 Across)
- Got a good reaction, as a joke (42 Across)
- Swim-bike-run race, for short (47 Across)
- Sound from someone sitting down at the end of a long day (48 Across)
- Game with Skip and Reverse cards (49 Across)
- "Here's my two cents, which might not amount to much …" (50 Across)
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